Ayesha Saleem Siddiqui, Akhtar Hayat, Mian Hasnain Nawaz, Muhammad Ashfaq Ahmad, Muhammad Nasir
Tracking and detection of biochemicals serves as a powerful tool for acquiring crucial information in a multitude of applications extending from environmental analysis to medical diagnosis. Long-term exposure or abnormal concentrations of some chemicals can cause serious health problems. Therefore, their rapid and sensitive detection is critical for academic and practical research purposes.
Graphene oxide (GO) is a promising chemically tunable platform for bioanalytical and optical sensing applications. It is of great interest to develop functionalized GO based sensors to buckle down the limitations of standard bioassays. Considering these facts, GO was modified with different metals and non-metals for recognition of analytes of interest. The constructed functionalized GO samples were studied using various surface characterization techniques. The catalytic and sensing properties of modified GO were investigated using optical: colorimetric and fluorometric methods, for the detection of diverse biochemicals.
Results advocate that the fabricated GO based optical sensors enabled high performance, cost-effective, and rapid quantitative detection of the target analytes with high sensitivity and selectivity in comparison to routine techniques. The findings in this work elucidate the prospects of modified GO for optical and biosensing applications.
